Note that the model does not include A BY B BY C, which is confounded with BLOCK W REPLIC. It is possible to test the ABC interaction if some interaction other than ABC is confounded in some of the replications. One possible layout would be that given in Table 1.26c. Table 1.26c Replication 1 Replication 2 Replication 3 Replication 4 Block Biock Block Biock l 2 1 | 2| 1 2 — 4 H 7] abc ab | b | ab ac ab 4 — a ac H a c () be b be | ac (i) abc a c 0) le [abc | b | ce | D | In replication 1, ABC is confounded with blocks. in replication 2, the AB interaction is confounded with blocks. For replications 3 and 4, AC and BC are confounded. For this example, A, B, and C are free of the block effects and three-fourths information for AB, AC, BC, and ABC can be obtained, since the unconfounded interactions can be estimated in three out of four of the replications. Hence we say AB, AC, BC, and ABC are partially confounded with blocks. The MANOVA specifications for this 2 x 2 x 2 factorial with partial confounding are MANOVA Y BY REPLIC(l.4), BLOCK(l,2).A, B, cf. 2)/ DESIGN